Experimental models of β-cell regeneration

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Experimental models of β-cell regeneration

The control of glucose metabolism by pancreatic endocrine cells throughout life relies on a tight regulation of the mass of insulin-producing beta-cells. How this homoeostasis is achieved is not well understood. Over the last few years, experimental rodent models with altered beta-cell mass, and, more recently, new transgenic approaches designed to tackle this problem, have provided abundant in...

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ژورنال

عنوان ژورنال: Biochemical Society Transactions

سال: 2008

ISSN: 0300-5127,1470-8752

DOI: 10.1042/bst0360286